Improved Foot Sensitivity And Pain Reduction In Patients With Peripheral Neuropathy After Treatment With Monochromatic Infrared Photo Energy—MIRE**

Understanding the Impact of Monochromatic Infrared Photo Energy on Peripheral Neuropathy

Peripheral Neuropathy (PN) is a common condition characterized by a disturbance of skin sensation, often manifesting as pain, numbness, or tingling, particularly in the feet. While various treatments have been explored over the years, recent studies are shining a light on the potential of Monochromatic Infrared Photo Energy (MIRE) to significantly improve foot sensitivity and reduce neuropathic pain in patients suffering from this condition.

The Groundbreaking Study

A comprehensive review of medical records from 2,239 patients, with an average age of 73 years, revealed that a significant number of these individuals were battling established peripheral neuropathy. Notably, diabetes was identified as the primary cause of PN in 62% of these cases. The research focused on the efficacy of MIRE treatment and its association with increased foot sensitivity, as measured by the Semmes Weinstein monofilament (SWM) 5.07, and a reduction in neuropathic pain.

Key Findings

Before the intervention, most patients exhibited a loss of protective sensation, defined by Medicare as a loss of sensation at two or more sites on either foot. Remarkably, after receiving MIRE treatment, the average number of insensate sites decreased significantly, showcasing an improvement of 66%. This substantial enhancement in foot sensitivity was accompanied by a dramatic reduction in pain levels, as assessed on an 11-point visual analogue scale, with patients experiencing a 67% reduction in pain.

The Mechanism Behind MIRE

MIRE works by delivering near-infrared photo energy to the feet, a method that has shown to temporarily increase foot sensitivity in patients with impaired sensation due to PN. The therapy involves using devices that emit light through superluminous diodes, which are applied directly to the affected areas, facilitating an improvement in sensory function and a decrease in discomfort.

Wider Implications

This study’s findings are pivotal as they challenge the long-held belief that sensory impairments associated with PN, especially due to diabetes, are irreversible. By demonstrating that MIRE treatments can significantly improve both foot sensitivity and reduce neuropathic pain, this research offers hope to millions suffering from this debilitating condition.

Clinical Applications

The implications of these results are far-reaching, particularly for diabetic patients who are at a higher risk of foot wounds and nontraumatic lower extremity amputations. By improving foot sensitivity, MIRE treatment not only enhances quality of life but also reduces the risk of injuries that patients might not otherwise detect due to their condition.


The consistent and robust improvements observed in patients treated with MIRE underline the therapy’s potential as a significant advancement in managing peripheral neuropathy. The correlation of these findings with previous studies further confirms the efficacy of this treatment approach.

The study highlights the need for continued exploration into non-surgical, non-pharmacological options for managing neuropathy and suggests that MIRE therapy could be a cornerstone in the future treatment landscape for this challenging condition.

By adopting such innovative therapies, healthcare providers can offer new hope to patients, significantly improving their quality of life and potentially reducing the need for more invasive treatments.

This study explored the effects of monochromatic infrared photo energy (MIRE) treatment on foot sensation and neuropathic pain in patients with peripheral neuropathy (PN).

The findings showed that MIRE treatment significantly improved foot sensitivity and reduced neuropathic pain, suggesting its potential as an effective therapeutic option for managing PN-related symptoms.

Read Full Article:   Https://Pubmed.Ncbi.Nlm.Nih.Gov/16504836/

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